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Hyperthyroidism - Medical Animation

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Hyperthyroidism - Medical Animation
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Hyperthyroidism - Medical Animation
The thyroid is the body's largest endocrine gland and is located anterior and lateral to the trachea and inferior to the larynx. One of the functions of the thyroid is to secrete thyroid hormone, which increases metabolic rate by increasing respiratory rate, increasing heart rate, accelerating breakdown of food for fuel, and increasing heat production. The thyroid hormone interacts with the hypothalamus and pituitary gland in a negative feedback loop to affect metabolic rate. Low levels of thyroid hormone in the blood cause the hypothalamus to release thyrotropin-releasing hormone. Thyrotropin-releasing hormone stimulates the anterior pituitary to release thyroid-stimulating hormone. Thyroid-stimulating hormone stimulates the thyroid gland to secrete thyroid hormones triiodothyronine, or T3, and thyroxine, or T4, into the bloodstream to affect cells throughout the body. The elevated levels of thyroxine in the blood are detected by the hypothalamus which stops production of thyrotropin-releasing hormone. This negative feedback loop keeps the metabolic rate from increasing too much. Hyperthyroidism is a condition in which there is a chronic high level of thyroid hormone present in the blood. The most common cause is Grave's disease, an idiopathic autoimmune disorder. In this condition, B cells in the thyroid mistakenly produce thyroid-stimulating immunoglobulins, which mimic the effect of thyroid-stimulating hormone and bind to the same receptor. As a result, binding these immunoglobulins stimulates the thyroid gland to continue producing thyroid hormone, which causes chronic manifestations of increased respiration, increased heart rate, called tachycardia, and increased heat production. In addition, the thyroid gland increases in size, resulting in a condition called thyroid hypertrophy or a goiter. Three common treatments of hyperthyroidism reduce circulating thyroid hormone. Antithyroid drugs such as propylthiouracil and methimazole suppress the synthesis of thyroid hormone. Surgical removal of thyroid tissue can reduce the amount of secreted thyroid hormone. Oral ingestion of radioactive iodine destroys thyroid tissue, resulting in decreased secretion of thyroid hormone. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"[I] have come to rely upon the Doe Report and your great staff of illustrators for all my medical malpractice cases. … Please know that I enthusiastically recommend you to all my colleagues.

Frank Rothermel
Bernhardt & Rothermel
"Medical illustrations are essential during trial for any medical malpractice case. The people at MLA have the uncanny ability of creating medical illustrations that simplify the most complex of medical concepts and human anatomy to a lay audience. The exhibits of MLA allow experts to easily describe complex concepts and human anatomy in a manner that could not be done otherwise.

In addition, their custom illustrations show in great detail the extent of injuries suffered and the devastating effects they have had on the client's anatomy. These custom illustration can show, side by side, the body before and after a catastrophic injury. The effect of this juxtaposition is unmatched by any testimony that can be adduced at the time of trial.

Even jurors after trial have commented on the ease with which they grasp medical concepts and anatomy once the MLA exhibits were introduced and used by my experts. Even judges who have "seen it all" are thoroughly impressed by the detail and sophistication of the illustrations.

I would not want to try a case without them."

Lambros Y. Lambrou
New York, NY

"Your firm is great to work with and, most importantly for me, you get the job done on time and with the utmost professionalism. You should be proud of all those you employ, from KJ to Ben B. I've been especially pleased over the years with the work of Brian and Alice, both of whom seem to tolerate my idiosycratic compulsion to edit, but I've not found a bad apple in the bunch (and, as you know, I've used your firm a bunch!). I look forward to our continued professional relationship."

Kenneth J. Allen
Kenneth Allen & Associates
Valparaiso, IN

"Thank you very much for the great work on the medical exhibits. Our trial resulted in a $16 million verdict for a 9 year old boy with catastrophic injuries, and the medical illustrations definitely played key role in the trial."

David Cutt
Brayton Purcell
Salt Lake City, UT

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