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Hypersensitivity - Medical Animation



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9/20/20
Hypersensitivity - Medical Animation
 
This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this animation for other purposes, click here.

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Hypersensitivity - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:
Our body protects us from many environmental substances such as pollen, foreign chemicals, and pathogens. The immune system is a surveillance system of specialized white blood cells and tissues that recognize self from foreign matter. An antigen is any foreign environmental substance that elicits an immune response. Antibodies are proteins developed by the immune system that recognize and bind antigens. Sometimes our immune system responds excessively to antigens, causing inflammation and tissue damage. This is called an allergic response. Antigens causing an allergic response are allergens. There are four major types of hypersensitivity, immediate, cytotoxic, immune complex, and delayed. The most common type of hypersensitivity is type one, or immediate. This type includes allergies elicited by antigens such as pollen. After initial exposure to this allergen, immune cells create immunoglobulin E antibodies for subsequent exposures. These antibodies are bound to certain white blood cells called mast cells and basophils. Immunoglobulin E encounters and binds to the allergen, triggering the release of inflammatory substances such as histamines, prostaglandins, and leukotrienes from mast cells and basophils. If severe and left untreated, type one can lead to anaphylaxis, an acute, life threatening condition that occurs quickly after antigen exposure and is characterized by low blood pressure and difficulty breathing. Treatment of type one hypersensitivity or allergic reactions induced by environmental substances or biological agents includes treatment of mild symptoms with over-the-counter antihistamines, corticosteroids, or immunosuppressive medications, treatment of severe reactions and anaphylaxis with an epipen, discontinued exposure to the environmental agent, and if the hypersensitivity is in response to a necessary drug treatment, substitution with another agent. In some cases, no reasonable alternative exists, in which case a regimen of desensitization by repeated and monitored exposure to low doses of the drug or agent may be necessary. ♪ [music] ♪

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"Whether it's demonstrating a rotator cuff tear, neck movement a few milliseconds after rear impact, or a proposed lumbar fusion, the Doe Report represents an instant on-line database of medical illustration for health-care and legal professionals.

Illustrations can be purchased 'as is' or modified within hours and sent either electronically or mounted on posterboard. An illustration is worth a thousand words, as juries perk up and look intently to capture concepts that are otherwise too abstract. Start with good illustrations, a clear and direct voice, a view of the jury as 12 medical students on day one of training, and your expert testimony becomes a pleasure, even on cross examination. An experienced trial lawyer should also emphasize these illustrations at the end of trial, as a means of visually reinforcing key concepts covered.

As a treating physician, I also use these accurate illustrations to educate my own patients about their medical conditions. The Doe Report is an invaluable resource, and its authors at MLA have always been a pleasure to work with."

Richard E. Seroussi M.D., M.Sc.
Diplomate, American Boards of Electrodiagnostic Medicine and PM&R
Seattle Spine & Rehabilitation Medicine
www.seattlespine.info

"Thank you for the splendid medical-legal art work you did for us in the case of a young girl who was blinded by a bb pellet. As a result of your graphic illustrations of this tragic injury, we were able to persuade the insurance company to increase their initial offer of $75,000.00 to $475,000.00, just short of their policy limits.

We simply wanted you to know how pleased we were with your work which, to repeat, was of superlative character, and to let you know that we would be more than willing to serve as a reference in case you ever need one. Many thanks for an extraordinary and dramatic depiction of a very serious injury which clearly "catapulted" the insurance company's offer to a "full and fair" amount to settle this case."

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Coulter &Coulter
Roanoke, VA

"We are extremely pleased with the quality of the medical exhibits and the timely manner in which they were provided. I will certainly recommend your company to my business associates who could benefit from your services. Please tell Brian Wilson [Director of Content Development, Senior Medical Illustrator] that he did an exceptional job on these exhibits."

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Dunaway and Associates
Anderson, SC

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Rockne Onstad
Attorney at Law
Austin, TX

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