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Hypersensitivity - Medical Animation



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6/5/20
Hypersensitivity - Medical Animation
 
This animation may only be used in support of a single legal proceeding and for no other purpose. Read our License Agreement for details. To license this animation for other purposes, click here.

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Hypersensitivity - Medical Animation
MEDICAL ANIMATION TRANSCRIPT:
Our body protects us from many environmental substances such as pollen, foreign chemicals, and pathogens. The immune system is a surveillance system of specialized white blood cells and tissues that recognize self from foreign matter. An antigen is any foreign environmental substance that elicits an immune response. Antibodies are proteins developed by the immune system that recognize and bind antigens. Sometimes our immune system responds excessively to antigens, causing inflammation and tissue damage. This is called an allergic response. Antigens causing an allergic response are allergens. There are four major types of hypersensitivity, immediate, cytotoxic, immune complex, and delayed. The most common type of hypersensitivity is type one, or immediate. This type includes allergies elicited by antigens such as pollen. After initial exposure to this allergen, immune cells create immunoglobulin E antibodies for subsequent exposures. These antibodies are bound to certain white blood cells called mast cells and basophils. Immunoglobulin E encounters and binds to the allergen, triggering the release of inflammatory substances such as histamines, prostaglandins, and leukotrienes from mast cells and basophils. If severe and left untreated, type one can lead to anaphylaxis, an acute, life threatening condition that occurs quickly after antigen exposure and is characterized by low blood pressure and difficulty breathing. Treatment of type one hypersensitivity or allergic reactions induced by environmental substances or biological agents includes treatment of mild symptoms with over-the-counter antihistamines, corticosteroids, or immunosuppressive medications, treatment of severe reactions and anaphylaxis with an epipen, discontinued exposure to the environmental agent, and if the hypersensitivity is in response to a necessary drug treatment, substitution with another agent. In some cases, no reasonable alternative exists, in which case a regimen of desensitization by repeated and monitored exposure to low doses of the drug or agent may be necessary. ♪ [music] ♪

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"Our practice involves medical negligence cases exclusively. We have six attorneys and one physician on staff. We have used Medical Legal Art's staff for every one of our cases over the past 12 years and have found their services to be extraordinary. The transformation of medical records into powerful graphic images has without fail been handled expertly, expeditiously and effectively translating into superb results for our clients, both in the courtroom and in settlement. Every case can benefit from their excellent work and we unqualifiedly recommend their services. They are the best!"

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Morrow and Otorowski
Bainbridge Island, Washington
www.medilaw.com

"At 3 PM it hit me--I needed exhibits of a tracheostomy, a coronary artery bypass and a deep vein thrombosis--all in time for a for-trial video deposition the next day. The Doe Report had each exhibit on line. In addition, I ran across an exhibit I hadn't even thought of: reduced ejection fraction after a heart attack. Because this was a video deposition, I could use the e-mail version of the medical exhibit, print it on my color copier, and let the camera zoom in. For $400, less than one blow-up by one of The Doe Report's competitors, I got four first-rate exhibits in less than a day. The Doe Report saved me time and money."

Tracy Kenyon Lischer
Pulley Watson King & Lischer
Durham, NC
www.PWKL.com

"I wanted to take some time out to let you know what a wonderful job you did with the 'collapsed lung/fractured rib' illustrations. They were both detailed and accurate. My medical expert was comfortable working with them and he spent at least an hour explaining to the jury the anatomy of the lungs, the ribs and the injuries depicted in the illustrations. Needless to say, the jury was riveted to the doctor during his testimony.

The jury returned a verdict for $800,000.00 and I'm sure we would not have done so well if not for the visualizations we were able to put forth with your assistance. Lastly, my special thanks to Alice [Senior Medical Illustrator] who stayed late on Friday night and patiently dealt with my last minute revisions."

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Proner & Proner
New York, NY

"For us, the defining feature of effective demonstrative evidence is whether, by itself, the piece will tell the story of the case. Medical legal Art provides our firm with illustrations and animations that are clear and persuasive. Their exhibits tell the story in a way that allows the jury to understand a very complex subject, very quickly."

James D. Horwitz
Koskoff, Koskoff & Bieder, P.C.
Bridgeport, CT

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