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Osteoporosis - Medical Animation

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Osteoporosis - Medical Animation
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Osteoporosis - Medical Animation
Bone consists of a dense, compact layer and a spongy cancellous structure. While compact bone forms an organized outer shell, cancellous bone consists of thin, interlocking plates, called trabeculae. Osteoblasts and osteoclasts are the osteocytes, or bone cells, that make up bone tissue. Bone continually renews its structure and strength through remodeling. Osteoclasts break down existing bone, and osteoblasts built up new bone. In normal bone, adequate physical stress and changing blood calcium levels prompt osteocytes to initiate bone remodeling. Osteoblasts emit a cytokine that transforms immature osteoclasts into mature osteoclasts. In a process called resorption, mature osteoclasts use enzymes to remove existing bone tissue. Then osteoclasts release chemicals that stimulate immature osteoblasts to mature and release osteoprotegerin, a protein that deactivates osteoclasts, stopping bone resorption. In response, bone formation occurs. Mature osteoblasts deposit osteoid, a matrix that contains minerals, such as calcium and phosphorous, and a strong, flexible protein called collagen. Calcium and phosphorus crystallize or mineralize the osteoid, then transform into sturdy hydroxyapatite crystals, completing the bone formation process. In both men and women, before mid-life, bone resorption and bone formation are balanced. Hormones and other factors influence bone remodeling. For example, estrogen hormone suppresses osteoclasts, inhibiting resorption to help maintain bone strength. After mid-life, estrogen levels fall, and osteoclast activity may go unchecked. Increased resorption can lead to bone loss. Osteoporosis is a progressive disease in which the rate of bone resorption exceeds bone formation. As a result, the trabeculae in cancellous bone become fewer and farther apart. The compact bone thins, and overall, the bone becomes weak, fragile, and prone to fractures. Treatments for osteoporosis include calcium and vitamin D supplements to help maintain blood calcium levels, anti-resorptive medications that promote bone strength by preventing osteoclast activation and excessive resorption, anabolic medications, which increase osteoblast activity and promote bone formation, and exercise, including weight-bearing activities, which adds stress to bone, promoting remodeling. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"Our firm was able to settle our case at an all day mediation yesterday and I am confident that the detail and overall appearance of the medical illustrations significantly contributed to the settlement. When we require medical illustrations in the future, I will be sure to contact [MLA]."

Noel Turner, III
Burts, Turner, Rhodes & Thompson
Spartanburg, SC

"I wanted to thank you for the terrific job you did illustrating my client's injuries. The case was settled at the pre-suit mediation, and I believe a good part of the success we had was due to the medical legal art you prepared.

Your work received the ultimate compliment at the conclusion of the mediation. The hospital risk manager took the exhibit with them at the conclusion of mediation, and will be using it to train nurses on how to prevent bed sores..."

Steven G. Koeppel
Troy, Yeslow & Koeppel, P.A.
Fort Myers, FL

"[I] have come to rely upon the Doe Report and your great staff of illustrators for all my medical malpractice cases. … Please know that I enthusiastically recommend you to all my colleagues.

Frank Rothermel
Bernhardt & Rothermel
"I wanted to take some time out to let you know what a wonderful job you did with the 'collapsed lung/fractured rib' illustrations. They were both detailed and accurate. My medical expert was comfortable working with them and he spent at least an hour explaining to the jury the anatomy of the lungs, the ribs and the injuries depicted in the illustrations. Needless to say, the jury was riveted to the doctor during his testimony.

The jury returned a verdict for $800,000.00 and I'm sure we would not have done so well if not for the visualizations we were able to put forth with your assistance. Lastly, my special thanks to Alice [Senior Medical Illustrator] who stayed late on Friday night and patiently dealt with my last minute revisions."

Daniel J. Costello
Proner & Proner
New York, NY

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