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Osteoporosis - Medical Animation

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Osteoporosis - Medical Animation
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Osteoporosis - Medical Animation
Bone consists of a dense, compact layer and a spongy cancellous structure. While compact bone forms an organized outer shell, cancellous bone consists of thin, interlocking plates, called trabeculae. Osteoblasts and osteoclasts are the osteocytes, or bone cells, that make up bone tissue. Bone continually renews its structure and strength through remodeling. Osteoclasts break down existing bone, and osteoblasts built up new bone. In normal bone, adequate physical stress and changing blood calcium levels prompt osteocytes to initiate bone remodeling. Osteoblasts emit a cytokine that transforms immature osteoclasts into mature osteoclasts. In a process called resorption, mature osteoclasts use enzymes to remove existing bone tissue. Then osteoclasts release chemicals that stimulate immature osteoblasts to mature and release osteoprotegerin, a protein that deactivates osteoclasts, stopping bone resorption. In response, bone formation occurs. Mature osteoblasts deposit osteoid, a matrix that contains minerals, such as calcium and phosphorous, and a strong, flexible protein called collagen. Calcium and phosphorus crystallize or mineralize the osteoid, then transform into sturdy hydroxyapatite crystals, completing the bone formation process. In both men and women, before mid-life, bone resorption and bone formation are balanced. Hormones and other factors influence bone remodeling. For example, estrogen hormone suppresses osteoclasts, inhibiting resorption to help maintain bone strength. After mid-life, estrogen levels fall, and osteoclast activity may go unchecked. Increased resorption can lead to bone loss. Osteoporosis is a progressive disease in which the rate of bone resorption exceeds bone formation. As a result, the trabeculae in cancellous bone become fewer and farther apart. The compact bone thins, and overall, the bone becomes weak, fragile, and prone to fractures. Treatments for osteoporosis include calcium and vitamin D supplements to help maintain blood calcium levels, anti-resorptive medications that promote bone strength by preventing osteoclast activation and excessive resorption, anabolic medications, which increase osteoblast activity and promote bone formation, and exercise, including weight-bearing activities, which adds stress to bone, promoting remodeling. ♪ [music] ♪

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What attorneys say about MLA and The Doe Report:
"The illustrations have consistently been well documented, accurate and timely. Most important though is that the illustrations demonstrate to juries and claims people the persuasive power of visual communication. Our firm has achieved multiple eight figure settlements and verdicts over the past ten years... Medical Legal Art has been there with us on every case."

Thomas C. Jones
Davis, Bethune & Jones, L.L.C.
Kansas City, MO

"There is nothing like a great graphic depicting the real nature and extent of a victim's injuries to get full value for your client. I use Medical Legal Art for mediations as well as trial."

Geoff Wells
Greene, Broillet, Panish & Wheeler
Santa Monica, CA

"It is with great enthusiasm that I recommend Medical Legal Art. We have used their services for three years and always found their professionalism, quality of work, and timely attention to detail to exceed our expectations. We recently settled two complicated catastrophic injury cases. One medical malpractice case involving a spinal abscess settled for 3.75 million and the other involving injuries related to a motor vehicle accident settled for 6.9 million. We consider the artwork provided by MLA to have been invaluable in helping us to successfully conclude these cases.

I highly recommend MLA to anyone seeking high quality, detailed medical legal artwork."

E. Marcus Davis, Esq.
Davis Zipperman, Krischenbaum & Lotito
Atlanta, GA

"Thank you for the splendid medical-legal art work you did for us in the case of a young girl who was blinded by a bb pellet. As a result of your graphic illustrations of this tragic injury, we were able to persuade the insurance company to increase their initial offer of $75,000.00 to $475,000.00, just short of their policy limits.

We simply wanted you to know how pleased we were with your work which, to repeat, was of superlative character, and to let you know that we would be more than willing to serve as a reference in case you ever need one. Many thanks for an extraordinary and dramatic depiction of a very serious injury which clearly "catapulted" the insurance company's offer to a "full and fair" amount to settle this case."

Philip C. Coulter
Coulter &Coulter
Roanoke, VA

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